abstract：:Daclizumab (DAC) is a molecularly engineered humanized IgGa monoclonal Ab directed against the alpha chain of the interleukin-2 receptor (IL2R). Inhibiting the amplification of the immune response by blocking IL2R can reduce the frequency of acute rejection without the attendant risk of infection. The purpose of this ...

journal_title：Clinical transplantation

authors： Rasaiah SB,Light JA,Sasaki TM,Currier CB

更新日期：2000-08-01 00:00:00

abstract：:Endothelium-dependent vasodilation in the peripheral circulation may be impaired in heart transplant recipients (HTx rec). Conflicting results have been obtained and the mechanisms involved have not been examined. In the present study, we examined whether long-time survivors of heart transplantation (Tx) show signs of...

journal_title：Clinical transplantation

authors： Holm T,Aukrust P,Andreassen AK,Ueland T,Brosstad F,Frøland SS,Simonsen S,Gullestad L

更新日期：2000-06-01 00:00:00

abstract：:Flow cytometric assay (FCA) was used to detect a cytomegalovirus (CMV) specific antigen (pp65) in CMV-infected fibroblast cells and in leukocytes of kidney recipients. FCA distinguished clearly between the infected and non-infected fibroblast cells. Regarding transplant patients, the FCA was positive when the number o...

journal_title：Clinical transplantation

authors： Essa S,Pacsa AS,Al-Attiyah R,El-Shazly A,Raghupathy R,Said T

更新日期：2000-04-01 00:00:00

abstract：:Infections are an important cause of mortality and morbidity in renal transplant recipients. To study the impact of anti-rejection therapy on the timing of infections, the records of 599 consecutive renal transplants, performed prior to 31 December 1996 at the Royal Melbourne Hospital, were reviewed. Patients were gro...

journal_title：Clinical transplantation

authors： Jamil B,Nicholls KM,Becker GJ,Walker RG

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Numerous studies of steroid withdrawal have been carried out in kidney and liver transplant recipients, but only a few in pancreas transplant recipients. Yet, pancreas transplant recipients could have significant long-term benefits from steroid withdrawal. METHODS:We performed a retrospective analysis to de...

journal_title：Clinical transplantation

authors： Humar A,Parr E,Drangstveit MB,Kandaswamy R,Gruessner AC,Sutherland DE

更新日期：2000-02-01 00:00:00

abstract：:Tacrolimus (TAC) is a useful immunosuppressive agent in the prevention of rejection. However, the blood level between its therapeutic and toxic levels is narrow such that its nephrotoxicity is a problem. Moreover, its bioavailability and pharmacokinetics are highly variable. We experienced a case of acute nephrotoxici...

journal_title：Clinical transplantation

authors： Watanabe S,Yamaguchi Y,Hattori M,Chikamoto H,Matsumoto N,Suzuki T,Oonishi M,Horita S,Tokumoto T,Tanabe K,Shiraga H,Toma H,Ito K

更新日期：2000-01-01 00:00:00

abstract：:The frequent scarcity of organ donors has made it necessary to consider transplantation of organs that may have the potential to transmit hepatitis B virus (HBV) to the recipient. Previous reports have documented the probability of infection of particular recipient populations with transplanted livers from hepatitis B...

journal_title：Clinical transplantation

authors： Dodson SF

更新日期：2000-01-01 00:00:00

abstract：:Sauropus androgymus (SA), a vegetable of the Euphorbiaceae family, is a common food source in Malaysia. In Taiwan, over 30 patients have developed progressive respiratory failure after consuming the extract from raw SA leaves as a means of losing weight. Symptoms consistent with a severe obstructive ventilatory defect...

journal_title：Clinical transplantation

authors： Luh SP,Lee YC,Chang YL,Wu HD,Kuo SH,Chu SH

更新日期：1999-12-01 00:00:00

abstract：:The aim of this study was to evaluate pancreatic function in total parenteral nutrition (TPN)-dependent children with permanent intestinal failure by measuring immunoreactive trypsinogen (IRT) levels. Between 1992 and 1996, 105 pediatric patients with permanent intestinal failure were referred to the Children's Hospit...

journal_title：Clinical transplantation

authors： Rovera GM,Sigurdsson L,Reyes J,Bouch LD,Naylor EW,Kocoshis SA

更新日期：1999-10-01 00:00:00

abstract：:Auxiliary liver transplantation (ALT) is known to correct liver-based metabolic disorders. However, it remains unclear whether the presence of a native liver influences the long-term prognosis of ALT for metabolic diseases. We reported on a 4-yr-old girl who had undergone living-related auxiliary partial orthotopic li...

journal_title：Clinical transplantation

authors： Komatsu H,Inui A,Fujisawa T,Sogo T,Miyagawa Y,Inui M,Uemoto S,Inomata Y,Tanaka K

更新日期：1999-08-01 00:00:00

abstract：:Vascular complications remain a significant source of morbidity after pancreatic transplantation. We describe a pseudoaneurysm of the superior mesenteric artery (SMA) with an arteriovenous fistula (AVF) involving the SMA and the superior mesenteric vein (SMV) discovered and treated surgically in the second week after ...

journal_title：Clinical transplantation

authors： Khan TF,Ciancio G,Burke GW 3rd,Sfakianakis GN,Miller J

更新日期：1999-06-01 00:00:00

abstract：:We report a 61-yr-old kidney transplant recipient with human Parvovirus B19 (HPV B19) infection presenting as a severe pancytopenia 1 month after transplantation. Bone marrow aspiration revealed severe erythroid hypoplasia with giant and dystrophic proerythroblasts. Bone marrow cells were positive for HPV B19 DNA dete...

journal_title：Clinical transplantation

authors： Marchand S,Tchernia G,Hiesse C,Tertian G,Cartron J,Kriaa F,Boubenider S,Goupy C,Lecointe D,Charpentier B

更新日期：1999-02-01 00:00:00

abstract：:The morphological characteristics of a kidney biopsy specimen taken 1 h after reperfusion of blood into the graft (1-h biopsy) during a cadaveric transplant operation were studied. The aim of the 1-h biopsy is to evaluate the pre-transplant risk factors for the delayed graft function, assess the renal function of the ...

journal_title：Clinical transplantation

authors： Oda A,Morozumi K,Uchida K

更新日期：1999-01-01 00:00:00

abstract：:Renal transplantation was performed in a 24-yr-old woman with type AA systemic amyloidosis. Renal biopsy at 11 yr post-transplantation showed no amyloid recurrence, but the presence of mesangial proliferative glomerulonephritis and focal segmental glomerular sclerosis. Renal function was satisfactory with the exceptio...

journal_title：Clinical transplantation

authors： Nishikido M,Koga S,Kanetake H,Saito Y,Harada T,Taguchi T,Matsuya F,Shindo K

更新日期：1999-01-01 00:00:00

abstract：:We herein report the first case of immunosuppression-associated thrombotic microangiopathy (TMA) in which an extrarenal graft was primarily affected by the characteristic microvascular lesions. Although TMA is a well-known complication of cyclosporine (CSA) or tacrolimus therapy in renal and extrarenal (liver, heart, ...

journal_title：Clinical transplantation

authors： Humar A,Jessurun J,Sharp HL,Gruessner RW

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:The shortage of grafts for kidney transplantation (Tx) has resulted in an expansion of criteria for pediatric donors. However, the limitations of pediatric donors for kidney Tx are not yet clearly established. We investigated the outcomes of recipients with pediatric kidney grafts from Colorado to elucidate ...

journal_title：Clinical transplantation

authors： Yagisawa T,Kam I,Chan L,Springer JW,Dunn S

更新日期：1998-12-01 00:00:00

abstract：:The use of tacrolimus (FK506) in adult kidney-transplant recipients has been the subject of a number of single- and multi-center studies. This review article focuses on those studies in which tacrolimus was used either as rescue therapy in patients who developed refractory rejection on cyclosporine (CyA)-based regimen...

journal_title：Clinical transplantation

authors： Laskow DA,Neylan JF 3rd,Shapiro RS,Pirsch JD,Vergne-Marini PJ,Tomlanovich SJ

更新日期：1998-12-01 00:00:00

abstract：:The purpose of this study was to evaluate the outcome of the medial segment of the graft after living related liver transplantation (LRLT). Of the 12 pediatric recipients who underwent LRLT, 2 received whole left liver graft, 1 left lateral segment graft, and 9 extended left lateral segment grafts. The hepatic veins o...

journal_title：Clinical transplantation

authors： Cheng YF,Chen CL,Haung TL,Lee TY,Chen TY,Chen YS,Liu PP,Chiang YC,Eng HL,Wang CC,Cheung HK,Jawan B,Goto S

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Angiotensin converting enzyme (ACE) inhibitors have been successfully used for treatment of proteinuria after renal transplantation (RTx). Factors possibly responsible for the great inter-patient variance of the antiproteinuric effect (APE) have not yet been investigated in renal-transplanted patients. METH...

journal_title：Clinical transplantation

authors： Lufft V,Kliem V,Hamkens A,Bleck JS,Eisenberger U,Petersen R,Ehlerding G,Maschek H,Pichlmayr R,Brunkhorst R

更新日期：1998-10-01 00:00:00

abstract：:The case of patient with glioblastoma metastatic to the peritoneal cavity 9 months after ventriculoperitoneal shunt surgery precluding cadaver organ procurement is presented. Even though central nervous tumors rarely metastasize spontaneously, the literature indicates that systemic metastases are related to previous s...

journal_title：Clinical transplantation

authors： Fecteau AH,Penn I,Hanto DW

更新日期：1998-08-01 00:00:00

abstract：:Mycophenolate mofetil (MMF) combined with conventional cyclosporine and steroids doses efficiently prevents acute rejection in kidney transplants. However, this regimen has been associated with an increased incidence of cytomegalovirus (CMV) disease and leukopenia, specially in patients receiving MMF at 3 g/d, suggest...

journal_title：Clinical transplantation

authors： Moreso F,Serón D,Morales JM,Cruzado JM,Gil-Vernet S,Pérez JL,Fulladosa X,Andrés A,Grinyó JM

更新日期：1998-06-01 00:00:00

abstract：:As experience with tacrolimus (FK506, Prograf) accumulates and reduced rejection rates are increasingly demonstrated, some transplant centers are adopting tacrolimus-based primary immunosuppressive regimens for their patients undergoing pancreas/kidney transplantation. The guidelines provided in this article based on ...

journal_title：Clinical transplantation

authors： Gruessner RW,Bartlett ST,Burke GW,Stock PG

更新日期：1998-06-01 00:00:00

abstract：:Acute renal failure (ARF) is a common and severe complication after liver transplantation (LT). The aim of this study was to ascertain the impact of ARF requiring dialysis in the outcome of LT and to analyze the risk factors leading to this event in the early post-operative period. From October 1988 to December 1994, ...

journal_title：Clinical transplantation

authors： Bilbao I,Charco R,Balsells J,Lazaro JL,Hidalgo E,Llopart L,Murio E,Margarit C

更新日期：1998-04-01 00:00:00

abstract：:The objective of this study was to evaluate the effects of itraconazole as a first choice drug in the treatment of pulmonary aspergillosis in heart transplant recipients. Heart transplant recipients suffering from invasive pulmonary aspergillosis were included in this study. Group 1 included 4 patients treated with i....

journal_title：Clinical transplantation

authors： Nanas JN,Saroglou G,Anastasiou-Nana MI,Kostis EB,Petrochilou-Paschou VP,Kontoyannis DA,Stamatelopoulos SF,Moulopoulos SD

更新日期：1998-02-01 00:00:00

abstract：:The potential influence of racially or ethnically diverse cultural perspectives on patient compliance with post-transplant treatments is discussed. Domains of competency regarding culturally sensitive clinical practice are outlined to assist providers in better understanding the perspectives that may influence the vie...

journal_title：Clinical transplantation

authors： Prieto LR,Miller DS,Gayowski T,Marino IR

更新日期：1997-12-01 00:00:00

abstract：:Cytokines, produced by both the recipient and the newly vascularized allograft, are central mediators in the inflammatory response to allografted tissue. This study examines the relationship between pre- and intraoperative levels of TNF, IL-1, IL-6, and IL-8 and hepatic allograft function in the early postoperative pe...

journal_title：Clinical transplantation

authors： Boros P,Suehiro T,Curtiss S,Sheiner P,Emre S,Guy S,Schwartz ME,Miller CM

更新日期：1997-12-01 00:00:00

abstract：:The purpose of this study was to compare CsA dose monitoring with trough levels (T0) vs. levels obtained 6 h after the morning dose of CsA (T6), with respect to the incidence of acute rejection and renal dysfunction, and the cumulative dose, as well as the cost of CsA after heart transplantation. Twenty consecutive ad...

journal_title：Clinical transplantation

authors： Cantarovich M,Besner JG,Fitchett DH,Latter DA

更新日期：1997-10-01 00:00:00

abstract：:Citrullinaemia is a rare autosomal recessive disorder due to a deficiency of argininosuccinate synthetase (ASS). While the clinical course of the adult onset form (Type II) is unpredictable, many patients undergo sudden deterioration with progressive cerebral oedema. Two patients with Type II citrullinaemia were refer...

journal_title：Clinical transplantation

authors： Kawamoto S,Strong RW,Kerlin P,Lynch SV,Steadman C,Kobayashi K,Nakagawa S,Matsunami H,Akatsu T,Saheki T

更新日期：1997-10-01 00:00:00

abstract：:The long-term side effects of lifelong steroid immunosuppression are well documented, therefore, steroid withdrawal (SW) if safe would clearly be of benefit. From 1987-1996, 470 kidney transplants were performed at our institution. During this time period, steroid withdrawal was offered to a select group of patients (...

journal_title：Clinical transplantation

authors： Sanfey H,Haussman G,Isaacs I,Ishitani M,Lobo P,McCullough C,Pruett T

更新日期：1997-10-01 00:00:00

abstract：:Although FK 506 has been shown to effectively reverse refractory renal allograft rejection, its ability to reverse accelerated renal allograft rejection as a primary agent has not been specifically addressed. Herein evidence of the ability of FK 506 to reverse accelerated renal allograft rejection is presented. A 16-y...

journal_title：Clinical transplantation

authors： Woodle ES,Newell KA,Haas M,Bartosh S,Josephson MA,Millis JM,Bruce DS,Piper JB,Aronson AJ,Thistlethwaite JR

更新日期：1997-08-01 00:00:00

abstract：:To define the etiology of anemia post-renal transplantation, we assessed hematologic parameters and EPO levels in 38 anemic and 16 non-anemic control renal transplant recipients (RTRs) with varying degrees of allograft function at periods > 3 months post-transplantation. Significant differences between the two groups ...

journal_title：Clinical transplantation

authors： Miles AM,Markell MS,Daskalakis P,Sumrani NB,Hong J,Sommer BG,Friedman EA

更新日期：1997-08-01 00:00:00

abstract：:This paper describes 108 consecutively treated patients receiving 109 cadaveric (CD) and living donor (LD) renal allografts using a protocol of quadruple sequential immunosuppression with a rabbit anti-human thymocyte IgG (Thymoglobuline), azathioprine, tapering corticosteroids, and delayed introduction of cyclosporin...

journal_title：Clinical transplantation

authors： Guttmann RD,Flemming C

更新日期：1997-06-01 00:00:00

abstract：:Although the kidney transplant program at this center has been active for the past 18 yr, five out of the seven cases of post-transplant lymphoma in kidney transplant patients were observed over the past 2 yr. During this period, we have shifted from cyclosporine to tacrolimus (FK506 or prograf) for maintenance immuno...

journal_title：Clinical transplantation

authors： Ciancio G,Siquijor AP,Burke GW,Roth D,Cirocco R,Esquenazi V,Byrne GE Jr,Miller J

更新日期：1997-06-01 00:00:00

abstract：:We analyzed the influence on allograft survival of pretransplant panel reactive antibodies (PRA) < 10%, PRA > 10%, autoantibodies, cold antibodies and a positive B cell crossmatch in 807 renal and 237 cardiac transplant recipients. Donors and recipients were predominantly of mixed ancestry (Khoi, San, Xhosa and Caucas...

journal_title：Clinical transplantation

authors： Creemers P,Brink J,Kahn D

更新日期：1997-04-01 00:00:00

abstract：:Endothelin-1 is a vasoconstrictor peptide released by the vascular endothelium by various chemical and mechanical factors. Cellular rejection is one of the most common complications following orthotopic liver transplantation, endotheliitis being its most specific and consistent histological feature. To assess the role...

journal_title：Clinical transplantation

authors： Fábrega E,Figols J,Dueñas C,Crespo J,Casafont F,Sanchez-Antolín G,de las Heras G,Amado JA,Pons-Romero F

更新日期：1997-02-01 00:00:00

abstract：:There is limited information regarding the role of flow cytometry crossmatching (FCXM) in primary cadaver kidney allografting and even less about B cell reactivity and graft survival (GS). Furthermore, there is little or no published data concerning reaction strength (cutoff value), the effect of historic sera reactio...

journal_title：Clinical transplantation

authors： LeFor WM,Ackermann JR,Alveranga DY,Bowers VD,Heinrichs DF,Kahana L,Shires DL Jr,Weinstein SS,Wright CE

更新日期：1996-12-01 00:00:00

abstract：:The donation of organs and tissues for the benefit of another person is an altruistic act and one that is a guaranteed option for the next-of-kin through various national Required Request legislations. At the Washington Hospital Center we have developed an approach that permits organ recovery from non-heart beating do...

journal_title：Clinical transplantation

authors： Kowalski AE,Light JA,Ritchie WO,Sasaki TM,Callender CO,Gage F

更新日期：1996-12-01 00:00:00

abstract：:Diabetic transplant recipients are at a high risk for foot pathology leading to amputation. This retrospective study from 1/85 to 2/95 examines the risk of foot complications in a population (n = 340) of diabetic renal and combined renal/pancreas transplant recipients. All groups suffered high lower extremity amputati...

journal_title：Clinical transplantation

authors： Kalker AJ,Pirsch JD,Heisey D,Sollinger HW,Belzer FO,Knechtle SJ,D'Alessandro AM

更新日期：1996-12-01 00:00:00

abstract：:The benefits of HLA matching have been clearly demonstrated in renal and cardiac transplantation. Recent studies suggest that HLA matching may be associated with improved survival rates for transplantation as well. However, the effect of HLA matching for lung transplantation has not been clearly demonstrated. Despite ...

journal_title：Clinical transplantation

authors： McGee C,Fox MD,Loyd JE

更新日期：1996-12-01 00:00:00

abstract：:The stress, coping resources, and family functioning of 36 mothers of children awaiting transplantation were evaluated. Using standardized assessment techniques, we found that, overall, 20% of mothers reported clinically elevated stress responses and that parenting stress was higher for mothers of children evaluated f...

journal_title：Clinical transplantation

authors： Rodrigue JR,Hoffmann RG 3rd,MacNaughton K,Graham-Pole J,Andres JM,Novak DA,Fennell RS

更新日期：1996-10-01 00:00:00